Detective Charlie Hudson teams up with what he calls his "highly trained law enforcement animal", a German Shepherd dog named Rex who he prefers to team up with because he doesn't talk his ear off.
When two hikers are discovered murdered near a remote coastal trail, the team is on the hunt for a fugitive duo wanted in a series of grisly campsite murders.
The team uncovers distorted loyalties that form when personal ties meet the trappings of fame when a troubled young pop star is suspected of killing her fiance.
After a journalist is killed searching for buried pirate treasure, Charlie and Rex dig deep into the competitive world of treasure-hunters to unearth the killer.
While Sarah embarks on a wilderness adventure, Charlie and Rex investigate the murder of a college professor.
A stock market guru's fortune is stolen, setting Charlie and Rex on the trail of a very surprising thief...
After a truck transporting liquid explosive is hijacked by criminals, Charlie and Rex must race against time to prevent the case from blowing sky high.
As Major Crimes investigates a dark web marketplace, Charlie and Rex protect a witness in their home.
After an elite hockey prospect is found dead, Charlie and Jesse disagree over the prime suspect in the case.
The Major Crimes team is forced to turn against Jesse when he becomes the prime suspect in a bank robbery.
After a raw diamond is found at the scene of a murder, Major Crimes sets up a stakeout to take down the suspected gem smugglers.
Charlie and Rex receive an award for heroism while Major Crimes investigates an extremist threat.
Charlie, Rex and Sarah visit an island community caught up in a resettlement dispute. Donovan tries to stop a British police officer from derailing the investigation.
Rex's starring role in a television commercial is interrupted by the murder of one of the agency's ad executives.
After the owner of a construction company is found dead, Charlie and Rex track the killer to an underground casino. Major Crimes goes undercover to solve the case.
While St. John's celebrates Mardi Gras, Charlie and Rex investigate a targeted killing spree.
When an officer and her K9 partner are violently attacked responding to a call, Major Crimes is at the ready, but their hearts are heavy as the case hits close to home.