Detective Charlie Hudson teams up with what he calls his "highly trained law enforcement animal", a German Shepherd dog named Rex who he prefers to team up with because he doesn't talk his ear off.
When Sarah bumps into Charlie and Rex on a day off, Charlie recounts the first case that he and Rex ever solved together.
Charlie and Rex are on the hunt after a prison van crash frees convicted killer Danny Winters. After tracking the fugitive, Charlie and Rex find themselves held hostage.
When a seemingly ancient body is discovered in Newfoundland's tundra, Charlie and Rex head into the wilderness in search of a reclusive survivalist community.
Deep under the Atlantic Ocean, a scuba diver's oxygen supply is severed. After his body washes ashore, Charlie and Rex wade into a mystery deeper than the sea itself.
After a socialite narrowly escapes being poisoned, Charlie and Rex uncover a string of suspects - including an old flame of Jesse's.
When a young woman is abducted from the place her friend was murdered two years earlier, Charlie and Rex discover she was trying to solve the cold case.
Rex is on trial after his DNA is discovered at the scene of the murder of Donovan's former police informant.
Charlie and Rex investigate a fairytale-turned-nightmare when a princess performer suspiciously dies at a child's birthday party.
Charlie and Rex are in grave danger as they find themselves captives of a kidnapper seeking vengeance.
When an arsonist begins terrorising a neighbourhood with car bombs, Charlie and Rex race to find the next target before the case goes up in smoke.
When a murder appears to mimic an infamous crime spree from the past, Charlie and Rex rush to stop the culprit from continuing a serial killer's legacy.
Charlie lets Rex take the lead as they investigate a murder at a prestigious dog show.
Trapped in an isolated mansion during a storm, Charlie and Rex must uncover a wannabe-killer after the hostess is drugged, while Sarah fights to keep her alive.
After Jesse's close friend vanishes, Charlie and Rex discover the man was living two separate lives.
When a magician dies during a practice-run of her latest routine, Charlie and Rex must look beyond the smoke and mirrors to uncover the truth.
Charlie and Rex witness an armed robbery during a trip to the bank, and soon discover a connection to a string of ingenious unsolved heists.