Agent Dwayne `King' Pride has a team out of New Orleans' NCIS field office, investigating crimes that affect military personnel. He's a local guy with a drive to do the right thing and leads agents Christopher LaSalle - who plays almost as hard as he works - and Meredith `Merri' Brody - a charismatic interrogator who has transferred to the `Big Easy'. Eccentric coroner Dr Loretta Wade supports them on cases. Together they delve into the dark side of the colourful city that's a magnet for servicemen on leave.
Pride is obliged to cut his holiday short when Hannah is suspended for breaking protocol during a joint investigation with the FBI.
The team investigates the crash of a private plane after a Navy pilot claims to have seen an unidentified object prior to the incident.
Pride travels to New York City after new DNA evidence is linked to a 20-year-old cold case from his time at the Jefferson Parish sheriff's office.
The team uncovers a sinister plot by a private detention centre contracted by the government to house undocumented immigrants.
Navy lieutenant Max Landry asks the field office for help when he suspects his girlfriend is a spy, while LaSalle faces another dead end as he searches for his brother.
Lasalle hopes to avenge his brother's murder by tracking the people involved in a drug ring in Alabama he believes is responsible, while Pride crosses paths with Eddie Barrett.
Following a natural gas explosion at a movie theatre, the team discovers the gas company has been hacked and more explosions could be triggered.
Sebastian calls the team in to assist with a possible kidnapping case when a dignitary's son he was assigned to protect disappears from a concert.
After Eddie Barrett provides an alibi witness, Pride and the team are more determined than ever to find a break in the case and avenge LaSalle's murder.
Pride is cut off from the team and backed into a corner after the investigation into Eddie Barrett uncovers a malicious plot.
The team is concerned when Sebastian becomes unreachable while undercover as a new recruit for an organization specializing in coordinated terrorist attacks.
The team tracks down a mysterious female assassin responsible for murders in Athens, Rome and London. Wade's son begs her to allow him to go on a police ride-along.
The team investigates the murder of a JAG captain who was discovered at home by his daughter, the only heir to his large estate.
When Pride is unable to sleep due to continuing nightmares about the mysterious man in the red suit, he undergoes a specialised treatment to help him.
Tammy must protect a research-obsessed teenage girl after her father is shot in their home, while the rest of the team searches for a motive.
When a man impersonating Lasalle attempts to free a young woman from jail, the team investigates both the imposter and the prisoner.
Racial tensions rise in New Orleans when a white NOPD officer shoots a black Navy officer he believed was armed in the middle of a busy street party.
When a sailor is found dead, the team tracks the suspicious movements of people in his life. Hannah comes to terms with her daughter's relationship with her ex's girlfriend.
When Sebastian is injured while unsuccessfully trying to prevent a kidnapping, NCIS races to find the missing woman and her abductors.
The team investigates the death of a Naval microbiologist whose hobby as a 'myth buster' resulted in his death at the hands of a legendary bayou creature.