Agent Dwayne `King' Pride has a team out of New Orleans' NCIS field office, investigating crimes that affect military personnel. He's a local guy with a drive to do the right thing and leads agents Christopher LaSalle - who plays almost as hard as he works - and Meredith `Merri' Brody - a charismatic interrogator who has transferred to the `Big Easy'. Eccentric coroner Dr Loretta Wade supports them on cases. Together they delve into the dark side of the colourful city that's a magnet for servicemen on leave.
An army convoy is attacked while crossing a bridge, and the state-of-the-art guided missile under its guard stolen during the ensuing commotion.
A blogger who devoted his energies to exposing corruption within government is found dead, having recently cited some Navy Seals as overstepped the mark in their use of force.
The team's help is called for when the Navy's finest female pilot dies at an air show while demonstrating a state-of-the-art aircraft about to be brought into service.
The team investigates the murder of a drone pilot who was apparently looking for evidence that someone did not want to be discovered.
An agent from the Royal Australian Navy disrupts Pride's investigation into the death of an Australian lieutenant killed on US soil.
The annual Red Dress Run is brought to a halt by the discovery of the body of a petty officer, whose death is linked to a new drug sweeping through the city.
The team investigates the murder of two US Navy foremen transporting a donor heart, and it soon becomes clear the organ has been stolen by a criminal in need of a transplant.
An accountant willing to give evidence against a weapons trafficker is killed before he can testify, and Pride resolves to ensure another witness does not meet the same fate.
A man is killed during a city-wide blackout, and the team suspects his death is connected to opportunist thieves using the power cut as cover for a looting spree.
A US Marine, a waitress and a chef are shot dead at a diner, and LaSalle realises the culprit may be the same killer he and Pride failed to catch during their first case.
A Navy Commander's wife is killed at home during a robbery, and when the team tracks one of the stolen items, they find it in the possession of Dr Wade's adopted son Danny.
Crossover with the original NCIS series. Ellie Bishop heads to New Orleans to help Pride track down the person responsible for the aircraft murders.
An immigrant petty officer dies in an apparent suicide, though Loretta finds finger-marks around the neck that suggest he was strangled before being thrown off a bridge.
Pride and Mayor Hamilton are kidnapped by an unknown assailant during New Orleans' Mardi Gras festivities.
The team searches for a soldier believed to have been a prisoner of war in Afghanistan, after his prints are found in a crime scene.
The murder of a petty officer on a US Navy construction site leads Pride to a drugs cartel, but when he launches a sting, he discovers Sonja among the dealers.
After a radio show DJ overhears the murder of a US Navy captain via an on-air call, the killer threatens her life and the team must keep her safe while chasing the culprit.
Brody thinks that a sailor hit by a party bus in the French Quarter is connected to her sister's death when similarities between the two emerge.
The team tackles the militia that has been targeting Pride head-on after his student daughter Laurel is attacked while out jogging on campus.
A naval psychologist is found dead near the route of a traditional New Orleans funeral procession, and when the agents investigate, they are dragged into a complex plot.
A US Navy lieutenant dies from arsenic poisoning in an Army general's hotel suite, and when Pride investigates, two very plausible motives for murder emerge.
A naval chef is seriously injured when her family's 100-year-old restaurant in the French Quarter is bombed, and the team's investigation threatens to uncover a secret.
The body of a master diver washes ashore, and when Homeland Security agent John Russo arrives in town, the death is linked to a possible incursion by a foreign aggressor.
A bomb is detonated in the city, and when Russo reveals Homeland Security was aware of the threat, Brody must ask some probing questions about his agenda.