Executive producer Dick Wolf adds another Chicago-centric series to his roster, this time focusing on the city's most explosive hospital and its staff of doctors and nurses -- a world first glimpsed in the `I Am the Apocalypse' episode of `Chicago Fire'. Relationships are forged in the chaos of the emergency room, where the team tackles cases inspired by topical events. Familiar faces from the city's police (`Chicago PD') and fire departments make appearances on the series.
When a commuter ship capsizes, the ED finds itself under water as the staff struggles to treat the influx of new patients. (S10, ep 1)
Lenox continues to rankle Archer as the two tackle their new roles and Ripley faces possible suspension. (S10, ep 2)
Asher treats a woman whose undiagnosed condition threatens the lives of both her and her unborn child. Goodwin receives a chilling message. (S10, ep 3)
A familiar face returns. Ripley and Charles treat a woman with a rare disorder. Frost suspects his patient's father is lying. (S10, ep 4)
Halloween chaos takes over the ED, as Hannah helps a pregnant woman with an autistic son. Charles clashes with nurse Jackie on a psych case. (S10, ep 5)
Goodwin's security is stepped up after she receives online threats. Archer and Frost treat disciplinary camp victims. (S10, ep 6)
Ripley and Frost uncover shocking information that conflicts with their patient's DNR. Asher facilitates an unexpected reunion. (S10, ep 7)
Goodwin's troubles persist. Charles clashes with his former resident over a patient. Lenox and Ripley treat a car accident victim. (S10, ep 8)
The team try to save one of their own. Frost and Abrams clash with a patient. Asher helps with an ectopic pregnancy. (S10, ep 9)
An army of surgeons tries to separate conjoined twins. Asher reconnects with someone from her past. Archer treats a boss with a heart problem. (S10, ep 10)
In the Trenches - Part II: After a subway tunnel caves in, Ruzek and Kidd help injured passengers. Part two of three. (S10, ep 11)
Goodwin deals with trauma from her assault while Ripley handles an overprotected patient. A staff member's error puts their position at risk. (S10, ep 12)
Lenox's mentorship is tested. Asher helps a woman with an ectopic pregnancy. Ripley's behaviour escalates. (S10, ep 13)
Gaffney meets a National Accreditation Board of Hospitals representative. Asher and Naomi cure a girl's infection. (S10, ep 14)
Ripley struggles to rescue a woman and her daughter trapped in an abandoned well. An old friend from Frost's TV days shadows Maggie. (S10, ep 15)
When a patient returns, Goodwin learns that time doesn't heal all wounds. Lenox and Abrams help a woman who has been in a coma for 20 years. (S10, ep 16)
Charles and Archer care for a heart recipient convinced his transplant has rejected his body. Hannah finds an ovarian mass in a pregnant patient. (S10, ep 17)
Asher makes a big call, Frost and Ripley treat a boy with a bite and Naomi handles a patient on their own. (S10, ep 18)
Maggie and Sharon's friendship is tested in contract talks. Archer and Ripley treat a skateboarder. (S10, ep 19)
Nurses' mass sick-out creates a hospital crisis. Archer and Frost compete over patient discharges. Charles struggles with a patient. (S10, ep 20)
Maggie and Frost compete for lungs for a patient. Asher awaits surrogacy results. Ripley and Morris care for a billionaire's daughter. (S10, ep 21)
Goodwin enforces the employee cuts, Charles' daughter is hospitalised and a patient makes a big decision. (S10, ep 22)