Detective Catherine Chandler is reunited with Dr Vincent Keller, a man who saved her from an assault that left her mother dead. They partner together to untangle the truth of her mother's murder.
When she was a teenager, Catherine 'Cat' Chandler witnessed the murder of her mother. Cat would have been killed too, but someone - or something - saved her.
When a rising young ballerina mysteriously falls to her death, Vincent senses that the understudy, Victoria, is hiding information about the dancer's murder.
A Bosnian immigrant is arrested on suspicion of killing a judge for deporting her brother. Vincent insists that Iris is innocent. Cat works behind the scenes to uncover the truth.
Vincent revives a 19-year old boy who was left for dead in a dumpster and rushes him to the E.R., where he remains in a coma.
Vincent is captured on a convenience store surveillance video while preventing a robbery.
Cat learns the truth about Vincent's blackouts and thinks he may be involved in the brutal murder of a local college fraternity brother.
Vincent mysteriously blacks out on his way to meet Catherine, and is now searching for answers.
Vincent allows JT to inject him with endorphins and sedatives that force him into a fugue state.
When Catherine's dad gets remarried, the bride-to-be and her bridesmaids try to find the daughter-of-the-groom a date for the wedding.
Vincent barely escapes being caught by his former fiancee Alex and must deal with the repercussions of his past.
J.T. learns that Evan is planning to propose a task force to catch the beast and must figure out how to stop him.
Cat suspects Muirfield might know Vincent's whereabouts and in spite of her vow to go cold turkey, she is forced to interrupt his romantic cabin getaway with Alex.
Cat and Vincent are unsure if they can trust Alex with the truth about his past.
Evan receives an interesting proposition that could change the course of his cross species investigation.
Suspicious that cases involving the vigilante are being mishandled, a new Assistant District Attorney arrives at the precinct wanting answers.
After taking their relationship to a new level, Cat and Vincent are forced to deal with reality when someone appears to be the framing the vigilante.
Cat is forced to reveal things that she had been keeping from Tess to salvage their relationship, and to protect Vincent.
Evan admits that he tipped off Muirfield to Vincent's whereabouts.
Gabe comes clean to Cat that he knows about Muirfield.
On the anniversary of her mother's death, Cat asks Gabe to attend her family's annual remembrance of Vanessa.
Cat and Vincent go on a date out in public in an attempt to be a normal couple.
When secrets about Cat's family are revealed, it will change everything Cat knew about her past.