Patrick Jane, adviser to the California Bureau of Investigation, is notorious for his unusual methods - not to mention his former career as a `psychic' - but the guy has a remarkable track record for solving serious crimes through uncanny powers of observation. That doesn't mean that Senior Agent Teresa Lisbon and her staff must be thrilled to have such an eccentric as a key member of the team.
The agents try to catch the killer of a woman who was accused of stealing $1million from her employer. Meanwhile, Teresa is taken off the Red John investigation.
Teresa and the team investigate the murder of state senator Melinda Baston's aide, while Patrick suspects the killing may have occurred due to political blackmail.
Teresa is accused of killing a child molester when her fingerprints are found on the murder weapon, but, unable to remember the incident, she asks Patrick for help.
Patrick and Teresa investigate the death of a biker gang's lawyer, and believe he was killed because he knew too many of his clients' secrets - but another motive is uncovered.
Witnesses believe supernatural forces could be to blame for an architect's death at his mansion, leading Patrick to uncover the truth behind the alleged paranormal activity.
Patrick is arrested after Bosco discovers the bug in his office, and has to investigate a murder case from the confines of his cell.
Bosco and Teresa team up to deal with a kidnapping, but suspect the victim's life could be in danger even if the ransom is paid - forcing Patrick to take drastic action.
Serial killer Red John attacks the CBI headquarters while Teresa's team is on assignment, leaving two agents dead and seriously wounding Bosco.
Patrick suspects an inside job when the agents are called to a robbery at a jewellery store. Meanwhile, Van Pelt and Rigsby consider the future of their relationship.
The murder of a baseball academy trainer leads Patrick to suspect the crime could have been motivated by money. He also has a flashback about life with his father.
A couple are murdered on their way to a high-school reunion, leading Patrick to connect the incident with a past case of bullying.
A corpse is unearthed at the opening of a new development in Salter, Central Valley, leading the team to suspect eco-terrorists - or the mayor - could be behind the murder.
The body of a saleswoman is found in the boot of a car at a luxury showroom - and although the agents soon believe they have found her killer, Patrick pursues another theory.
Cho is forced to revisit old haunts and confront his murky past as he investigates the fatal shooting of a reformed criminal who used to belong to the same gang as him.
A chef is poisoned during a culinary competition, leading the agents to question the other contestants, who they suspect were trying to sabotage the victim's chances of winning.
A scientist contacts Patrick for help after she was exposed to a deadly virus, and he discovers someone had tampered with the security systems at the facility where she works.
The team uncovers a plot to steal a priceless artefact from the British Museum, and new CBI boss Madeleine Hightower holds Teresa responsible for Patrick's rash behaviour.
The agents discover three dead bodies on a Native American reservation after a woman with amnesia is found near the scene. Hightower gives Rigsby and Van Pelt an ultimatum.
The agents arrest a hitman in connection with the recent murder of an Assistant District Attorney, but the trial falls apart, prompting Patrick to take matters into his own hands.
Patrick finds a new adversary in cult leader Bret Stiles, who arouses suspicion when a media mogul who may have questioned his group's activities is found dead.
The agents investigate the murder of a mathematical genius and discover he was working on a device that could make it possible to hack into any computer.
Self-proclaimed psychic Kristina Frye joins the team to help investigate the murder of the leader of an organisation dedicated to eradicating human trafficking.
Kristina Frye makes a televised appeal to Red John, bringing back dark memories for Patrick - who is forced to protect his rival from the ruthless serial killer.