Based on novels by Maureen Jennings, `Murdoch Mysteries' follows young detective William Murdoch. In a series of stories taking place in Toronto during the 1890s, several challenging murder cases arise. Murdoch uses up-and-coming forensics techniques and an unconventional approach, which often elicit skepticism from his fellow officers and his boss. Coroner Julia Ogden becomes Murdoch's number one ally, and they make a top-notch team, but he struggles against tradition and prejudice to solve some of the city's most gruesome murders.
When his aunt (Derry Girls' Siobhan McSweeney) foretells a dire fate, Crabtree leaves Effie at the altar. Murdoch investigates two murders at a cemetery.
Murdoch suspects Hart is hiding information about her dead father. Meanwhile, Brackenreid warns Watts that a PI is on his trail.
Murdoch suspects author Rudyard Kipling is involved in the murder of a writer at a convention.
Murdoch investigates the murder of a man found dead outside a burlesque show performed by Nina Bloom.
After a motorbike inventor drives over a cliff to his death, Murdoch suspects his innovative machine was sabotaged.
While out of town, Murdoch and Ogden investigate the suspicious death of a Mennonite.
Hours before a clandestine meeting between President Taft and Prime Minister Laurier, Murdoch gets a visit from Terence Meyers, followed by a suspicious death.
Murdoch investigates the brutal on-camera murder of an actress during the filming of a movie about a clown killer.
While honeymooning in England, Crabtree and Effie find a hotel guest's death suspicious.
As Murdoch investigates the murder of an elite athlete impaled by a javelin, Hart and Arthur plot her father's demise.
The sudden death of a key witness in a case leaves Murdoch physically unsettled.
Higgins enlists Watts' help after he messes up the courier delivery of a horse statue for some very dangerous thugs.
Murdoch must prove Brackenreid's innocence when he's framed for murder by a vengeful foe.
Murdoch investigates the stabbing murder of a doomsayer on the eve of a passing of Halley's Comet.
Murdoch suspects deceit and murder in the apparent drowning of a military recruit.
A logging camp co-worker from Murdoch's past seeks his help in exonerating him in a decades-old murder.
When Murdoch suspects a sequential killer is targeting hobos, he enlists Watts to go undercover with Crabtree.
Murdoch suspects that an art dealer's murder is linked to a cache of erotic drawings.
After Ogden is sentenced to three years in prison for the death of an alderman's wife, Murdoch pursues the cocky politician with a vengeance.
On the eve of her exoneration, Ogden has a tricky murder to solve. Meanwhile, Hart and Isaiah Buchanan investigate the death of a student at a black fraternity dance.
When the director of Toronto's new symphony is murdered, Murdoch suspects jealous musicians are responsible.
When a bride mysteriously collapses and dies before her wedding, Murdoch suspects she was poisoned by her perfume.
Murdoch's investigation of a constable's murder is hampered by interference from Brackenreid's over-zealous replacement.
Disgusted by the new inspector's tactics, Murdoch resigns and is privately enlisted to find a missing heiress.