The Powerpuff Girls have to protect Townsville from villains who want to take over the metropolis. The sisters have to manage their homework with their superhero activities.
After Mojo Jojo's latest creation threatens to blast him into tiny bits, the Powerpuff Girls are forced to take Mojo in.
The Fashionistas unveil their new perfume.
After being blasted by Duplikate Blossom turns into a triple threat.
In an effort to make himself "great," Mojo steals the powers that makes the each of the Powerpuff Girls the heroes they are.
When Morbucks realizes that The Powerpuff Girls see her as a villain and not a friend, she sets out to turn the town against them.
Ms. Keane is nervous about a first date.
When Morbucks falls in love she finds the first thing money can't buy.
When a mysterious raincloud plagues Townsville, Bubbles learns things aren't what they seem.
Buttercup is knocked off-kilter by a mysterious force.
When an ancient prophecy spells doom for Townsville, the girls must race to stop it.
After they get accused of a crime they didn't commit, The Powerpuff Girls and The Derbytantes have to find a way to clear their name!
The Powerpuff Girls compete in a race against some of their most vicious villains, to win whatever is in the Mayor's mysterious box of mystery.
After a chemical spill the girls and Mojo find themselves trapped together.
Buttercup must go it alone to save her family from a kidnapping.
When the professor is kidnapped, the girls must go to a mysterious island to save him.
After defeating Mojo for the umpteenth time, The Powerpuff Girls are confident they are unstoppable.
With Townsville in peril, the girls are sent to the arctic on a dangerous mission to find the key to saving the day.
The girls must enter a cursed jungle temple to obtain the last Heart Stone.
In the stunning conclusion, the girls learn that Lester has one more trick up his sleeve.
On Halloween Night Morbucks summons a monster that she didn't expect.
The girls must replace the Professor's Christmas present on Christmas Eve.
Buttercup is not a fan of Bubbles' newly created digital assistant.
When a mysterious new ice cream flavor takes Townsville by storm, the girls suspect there might be foul play
When Bliss brings a new tech product to town it's more powerful than imagined.
When the girls tell Barry he's a hero he takes it too far.
A new villain arrives in Townsville and gives the old villains an enticing offer.
A crash landing sends Townsville over the edge.
An alarmingly familiar cat burglar terrorizes Townsville.
When Buttercup loses the Professor's latest invention, she'll have to beat The Gangreen Gang at their own game to get it back.
The Professor makes new friends but they may be the wrong crowd.
Bubbles and Buttercup make a deal without realizing the consequences.
Buttercup is tired of Bubbles following her everywhere.
A new superhero arrives in Townsville with a dark secret.
A trip to the supermarket has bizarre consequences.
The school play goes off the rails when the drama teacher interferes.
The Powerpuff Girls are tasked with keeping a priceless gem safe from thieves.
With Man-Boy on the loose Donny must be prepared for anything.
When Princess Morbucks steals Octi, Bubbles' reaction surprises everyone, even her sisters.
When the Girls start playing soccer the Professor goes overboard.