The Powerpuff Girls have to protect Townsville from villains who want to take over the metropolis. The sisters have to manage their homework with their superhero activities.
After Bubbles wins two tickets to see the girls’ favourite band Blossom and Buttercup compete for her plus-one.
Buttercup starts spending a lot of time with her new friends a group of bad-girl skaters called The Derbytantes…
After going overboard on the candy Blossom and Buttercup wake up with no memory of last night and no idea where Bubbles is!
A mysterious rainbow causes everyone to become unhappy.
Bubbles convinces the Professor to test his new transmogrifying ray on her new friend Danny the Pony in an effort to help him become the unicorn.
When Man-Boy returns to exact his revenge, Buttercup must embrace the balance between punching and hugging in order to defeat him.
When the Mayor's assistant Ms. Belllum departs, the Girls become so busy that they accidentally hire the dangerous Bianca Bikini as his new assistant!
Buttercup steals Octi to teach Bubbles a lesson, but ends up wanting to keep him for herself.
Bubbles breaks her arm and gets a powerful robotic cast.
Buttercup and Bubbles discover they've "levelled up".
Bubbles' excitement over being a contestant in The Townsville Pageant is ruined when Blossom and Buttercup become overbearing stage-sisters.
Professor Utonium makes a potion so the girls look older!
After the Powerpuff Girls feel slighted by the Professor when he gets a new girlfriend, the Girls conspire to break them up.
When Blossom gets overzealous with spring cleaning, she accidentally unleashes a group of evil spirits.
Blossom will stop at nothing to impress a famous scientist.
When the coolest girl in school befriends the Powerpuff Girls, she charms them into becoming her accomplices in a series of adventurous crimes.
When a dainty princess on a mission comes to Townsville, the Girls must learn that the superhero way isn't always the right way.
When someone steals all the water in Townsville, it's up to the Girls to race through the Townsville Wastelands to get it back.
When the Amoeba Boys wreak havoc on the Internet, Bubbles has to hack her sisters in order to stop them.
When Bubbles gets a bad school photo, it sends her into an existential tailspin of darkness.
When Blossom and Bubbles get sick, Buttercup volunteers to take care of them for the day.
When Donny the Unicorn visits Bubbles becomes jealous of his new friend.
When Princess Morbucks enters the Student Body President race, Blossom sinks to her level to secure the win.
After finding a baby monster in the park, Bubbles insists on adopting it without considering the consequences!
When the Fashionistas launch a new line of brainwashing clothing, it's up to the Powerpuff Girls to stop the fashion trend before it's too late.
When the Girls try a "quick-fix" on their neglected veggie garden, they are left with a giant, mooching tomato worm that they must care for.
Bubbles realises she and the Professor don't have much in common so she schedules a road trip with just the two of them.
When the Professor's latest invention wreaks havoc in the house, it's up to the Powerpuff Girls to stop it before it escapes.
When Blossom can't join her favourite school club, she imagines what her life would be like if she joined other clubs.
When a series of negative articles about the Powerpuff Girls are posted on the Internet, the Girls track them back to Silico.
The girls get a Paper Fortune Teller that can predict the future if they tell it a secret. But soon it predicts the Powerpuff Girls will be destroyed!
The girls get into trouble when left to entertain themselves on a rainy day.
To escape a monster the girls have to tell him a scary story.
Buttercup gets more than she bargained for when she makes a deal with a cool '80s metalhead to get a sweet new guitar.
After the Professor's latest experiment goes awry, the Girls become overprotective.
When Morbucks loses her money Blossom tries to reform her.
After a snow day saves Blossom from having to face a boy who’s asked her out she decides to use her ice breath to keep it going.
When the Girls disobey the Professor and swing all the way over the swing set, they must deal with unexpected consequences.
Blossom neglects her promise to Bubbles when she takes on too many things, leaving Buttercup and Bubbles to fend for themselves.