Young war hero Angus `Mac' MacGyver has an extraordinary knack for unconventional problem solving and an extensive bank of scientific knowledge that he believes can best be put to use saving lives, both of which come in handy when he creates a clandestine organization within the United States government to tackle high-risk missions around the world. Working under the sponsorship of the Department of External Affairs, MacGyver quietly prevents disasters with the help of former CIA agent Jack Dalton.
Mac and the team infiltrate a glamorous hotel used as a hideout for criminals to find a woman with vital information on Codex. However, their target has a new secret identity, including a new face.
When Taylor's former protege is killed while preventing a bio-weapon from falling into the wrong hands, Mac and the team must find the weapon before it's sold to a terrorist cell.
When Russ is kidnapped, Mac and the team must break out a previously murderous psychopath, now pacifist, from prison to help find him. Mac and Desi confront their relationship issues.
Mac's meeting with Desi's parents goes sideways when her brother finds himself in trouble and desperately needs their help. Russ and Matty must ask an old nemesis for assistance.
Using a cryptic postcard as their only clue, Mac and the team must solve a fallen friend's final case and bring him justice.
During COVID's first stay-at-home order, as Mac, Bozer and Riley quarantine together, they try to stop a crime in progress at their neighbour's house.
The secret experimental cancer treatment Mac is developing with a friend is discovered when culprits ransack their lab, kidnap Mac's partner and plan to use the research to create a powerful new ne...
Mac and team rush to help after Matty's former mentor Ian Cain and his embassy staff come down with a deadly, mysterious illness.
When Mac and the team are unable to prevent Department of Defense intel from falling into Codex's hands, Mac must scale a vertical cliff to prevent the info's transmission.
Mac and the team discover Murdoc hacked their comms. Mac and the team must stop Murdoc, who is working to kill thousands and reveal each Phoenix member's most-guarded secrets.
Mac and Riley head overseas together to prevent a governmental collapse and inadvertently inhale new deadly microscopic technology.
Mac, Desi and Russ go undercover during a royal Indian wedding to protect a princess whose policies could put her life in danger.
While Mac and the team delve into the world of Italian car culture in order to track down a crime boss-in-hiding, Mac must lean on Desi when he discovers that he losing the ability to control his h...
Mac and Desi travel with Bozer to his childhood home when his aunt dies in a tragic accident, however, they soon discover she may have been murdered for trying to expose the city's contaminated wat...
When Mac and Riley go missing and wake up 24 hours later in a corn field with no memory of how they got there, they must unravel the mystery to find who took them.